Round 5 - Dificid

7 days after my 9 weeks of Vanco (last taken on 7/16), my C-Diff returned on Saturday 7/23. I called the infectious diseases on call Doctor at Methodist Hospital and again was prescribed Vanco. On Tuesday my primary Doctor called and ordered up a 10 day supply of Dificid, a new drug for Clostridium difficile. Kathee picked it up at the hospital last night and I started on it this morning. More on below

FDA approves treatment for Clostridium difficile infection


The safety and efficacy of Dificid were demonstrated in two trials that included 564 patients with CDAD that compared Dificid with vancomycin, a common antibiotic used to treat CDAD. The clinical response was similar in the Dificid group compared with the vancomycin group in both studies. In some patients with CDAD, symptoms can return. In the Dificid trials, a greater number of patients treated with Dificid had a sustained cure three weeks after treatment ended versus those patients treated with vancomycin.

“In recent years, many in the infectious disease community have seen an increase in the number of cases of people with a C. difficile infection,” said Edward Cox, M.D., M.P.H., director of the Office of Antimicrobial Products in the FDA’s Center for Drug Evaluation and Research. “Dificid is an effective new treatment option for patients who develop Clostridium difficile-associated diarrhea.”


Dificid was developed by San Diego-based Optimer Pharmaceuticals Inc.

The following represents how I am feeling:

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